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Silvia Melgar


Silvia Melgar

APC Microbiome Ireland - University College of Cork, Ireland

Biography

Silvia Melgar received her PhD in Immunology from Umeå University in Sweden, followed by a Postdoctoral Fellowship and a Senior Research Scientist position at AstraZeneca R&D Mölndal, Sweden. She is currently an APC Faculty Investigator under the Host - Microbe Dialogue Research theme in the APC Microbiome Ireland Research Institute of University College Cork (UCC), Ireland. She joined the APC in 2008 as a Principal Scientist under the GlaxoSmithKline-APC collaboration and became an Investigator in 2012. Her research interests include 1) the identification of novel molecular mechanisms associated to diet - host - bacteria interactions and their relevance to health and intestinal disorders such as inflammatory bowel disease (IBD) and colorectal cancer; 2) identification and pre-clinical evaluation of novel therapies for inflammatory and malignant conditions in the gastrointestinal tract in animal models and in in vitro cell systems.

Abstract

Abstract : The influence of diet, bacteria and bacterial metabolites on epithelial cell responses in intestinal inflammation and cancer